THYMIC PEPTIDES IN IMMUNE RECONSTITUTION AND CLINICAL OUTCOME AFTER ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION

Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation

Abstract: Patients with hematologic malignancies or nonmalignant diseases may undergo allogeneic hematopoietic cell transplantation (HCT), which represents a potential curative treatment.However, they are still at risk of life-threatening complications, such as relapse, acute graft-versus-host disease, and opportunistic infections.These complicatio

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Semantic SLAM Based on Improved DeepLabv3⁺ in Dynamic Scenarios

Simultaneous Localization and Mapping (SLAM) plays an irreplaceable role in the field of artificial intelligence.The traditional visual SLAM algorithm is stable assuming a static environment, but has lower robustness and accuracy in dynamic scenes, which affects its localization accuracy.To address this problem, a semantic SLAM system is proposed t

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Heteroduplex DNA position defines the roles of the Sgs1, Srs2, and Mph1 helicases in promoting distinct recombination outcomes.

The contributions of the Sgs1, Mph1, and Srs2 DNA helicases during mitotic double-strand break (DSB) repair in yeast were investigated using a gap-repair assay.A diverged chromosomal substrate was used as a repair template for the gapped plasmid, allowing mismatch-containing heteroduplex DNA (hDNA) formed during recombination to be monitored.Overal

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